PRDM10 Antibody

Product Specifications

Background

The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

NCBI Gene ID

56980

Swiss Prot

Q9NQV6

Accession Number

Q9NQV6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PRDM10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the Central region of human PRDM10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

130 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRDM10

NCBI Official Name

PR domain zinc finger protein 10

NCBI Organism

Homo sapiens

Background Reference 01

Bhatti, P., et al. Radiat. Res. 173 (2) :214-224 (2010)

Background Reference 02

Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

Background Reference 03

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 04

Siegel, D.A., et al. Int. J. Dev. Neurosci. 20 (3-5), 373-389 (2002) :

Other Product Names

PR domain zinc finger protein 10, 211-, PR domain-containing protein 10, Tristanin, PRDM10, KIAA1231, PFM7, TRIS

Tested Applications

Protein ID

442570289

Physical Properties

Liquid

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