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NET1 Antibody

Product Specifications

Background

NET1 acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway (By similarity) .

NCBI Gene ID

10276

Swiss Prot

Q7Z628

Accession Number

Q7Z628

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NET1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the Central region of human NET1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NET1

NCBI Official Name

Neuroepithelial cell-transforming gene 1 protein

NCBI Organism

Homo sapiens

Background Reference 01

Lee, J., et al. J. Biol. Chem. 285 (34) :26618-26627 (2010)

Background Reference 02

Carr, H.S., et al. J. Biol. Chem. 284 (36) :24269-24280 (2009)

Background Reference 03

Gilcrease, M.Z., et al. Cancer Epidemiol. Biomarkers Prev. 18 (1) :80-86 (2009)

Background Reference 04

Murray, D., et al. Br. J. Cancer 99 (8) :1322-1329 (2008)

Other Product Names

Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8, NET1, ARHGEF8

Tested Applications

WB

Protein ID

52782735

Physical Properties

Liquid

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