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ANP32C Antibody

Product Specifications

Background

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq].

NCBI Gene ID

23520

Swiss Prot

O43423

Accession Number

O43423

Host

Rabbit

Reactivity

Human

Immunogen

This ANP32C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the Central region of human ANP32C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-136

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ANP32C

NCBI Official Name

Acidic leucine-rich nuclear phosphoprotein 32 family member C

NCBI Organism

Homo sapiens

Background Reference 01

Matilla, A., et al. Cerebellum 4 (1) :7-18 (2005)

Background Reference 02

Kochevar, G.J., et al. Hum. Mutat. 23 (6) :546-551 (2004)

Background Reference 03

Fan, Z., et al. Nat. Immunol. 4 (2) :145-153 (2003)

Background Reference 04

Kadkol, S.S., et al. Breast Cancer Res. Treat. 68 (1) :65-73 (2001)

Other Product Names

Acidic leucine-rich nuclear phosphoprotein 32 family member C, Phosphoprotein 32-related protein 1, Tumorigenic protein pp32r1, ANP32C, PP32R1

Tested Applications

WB

Physical Properties

Liquid

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