NUP43 Antibody

Product Specifications

Background

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]) .

NCBI Gene ID

348995

Swiss Prot

Q8NFH3

Accession Number

Q8NFH3

Host

Rabbit

Reactivity

Human

Immunogen

This NUP43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-171 amino acids from the Central region of human NUP43.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NUP43

NCBI Official Name

Nucleoporin Nup43

NCBI Organism

Homo sapiens

Background Reference 01

Zuccolo, M., et al. EMBO J. 26 (7) :1853-1864 (2007)

Background Reference 02

Glavy, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (10) :3811-3816 (2007)

Background Reference 03

Loiodice, I., et al. Mol. Biol. Cell 15 (7) :3333-3344 (2004)

Background Reference 04

Le Rouzic, E., et al. J. Biol. Chem. 277 (47) :45091-45098 (2002)

Other Product Names

Nucleoporin Nup43, Nup107-160 subcomplex subunit Nup43, p42, NUP43

Tested Applications

Protein ID

27923819

Physical Properties

Liquid

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