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WDR68 Antibody

Product Specifications

Background

WDR68 is involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity) . Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

NCBI Gene ID

10238

Swiss Prot

P61962

Accession Number

P61962

Host

Rabbit

Reactivity

Human

Immunogen

This WDR68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human WDR68.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-117

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DCAF7

NCBI Official Name

DDB1- and CUL4-associated factor 7

NCBI Organism

Homo sapiens

Background Reference 01

Ritterhoff, S., et al. EMBO J. 29 (22) :3750-3761 (2010)

Background Reference 02

Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)

Background Reference 03

Morita, K., et al. J. Dermatol. Sci. 44 (1) :11-20 (2006)

Background Reference 04

Jin, J., et al. Mol. Cell 23 (5) :709-721 (2006)

Other Product Names

DDB1- and CUL4-associated factor 7, WD repeat-containing protein 68, WD repeat-containing protein An11 homolog, DCAF7, HAN11, WDR68

Tested Applications

WB

Protein ID

48428729

Physical Properties

Liquid

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