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AOAH Antibody

Product Specifications

Background

This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.

NCBI Gene ID

313

Swiss Prot

P28039

Accession Number

P28039

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This AOAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human AOAH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

65 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AOAH

NCBI Official Name

Acyloxyacyl hydrolase

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Pelak, K., et al. J. Infect. Dis. 201 (8) :1141-1149 (2010)

Background Reference 03

Barnes, K.C., et al. J. Allergy Clin. Immunol. 118 (1) :70-77 (2006)

Background Reference 04

Coulthard, M.G., et al. Infect. Immun. 64 (5) :1510-1515 (1996)

Other Product Names

Acyloxyacyl hydrolase, Acyloxyacyl hydrolase small subunit, Acyloxyacyl hydrolase large subunit, AOAH

Tested Applications

WB

Protein ID

113976

Physical Properties

Liquid

Frequently Asked Questions

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