Mouse Tgfbr2 Antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

NCBI Gene ID

21813

Swiss Prot

Q62312

Accession Number

Q62312

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Tgfbr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-575 amino acids from the C-terminal region of mouse Tgfbr2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

67 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Tgfbr2

NCBI Official Name

TGF-beta receptor type-2

NCBI Organism

Mus musculus

Background Reference 01

Droguett, R., et al. Exp. Cell Res. 316 (15) :2487-2503 (2010)

Background Reference 02

Robson, A., et al. Dev. Dyn. 239 (9) :2435-2442 (2010)

Background Reference 03

Moreno, S.G., et al. Dev. Biol. 342 (1) :74-84 (2010)

Background Reference 04

Ouyang, W., et al. Immunity 32 (5) :642-653 (2010)

Other Product Names

TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, Tgfbr2