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DDX56 Antibody

Product Specifications

Background

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit.

NCBI Gene ID

54606

Swiss Prot

Q9NY93

Accession Number

Q9NY93

Host

Rabbit

Reactivity

Human

Immunogen

This DDX56 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human DDX56.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

62 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DDX56

NCBI Official Name

Probable ATP-dependent RNA helicase DDX56

NCBI Organism

Homo sapiens

Background Reference 01

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 02

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 03

Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

Background Reference 04

Lehner, B., et al. Genome Res. 14 (7) :1315-1323 (2004)

Other Product Names

Probable ATP-dependent RNA helicase DDX56, ATP-dependent 61 kDa nucleolar RNA helicase, DEAD box protein 21, DEAD box protein 56, DDX56, DDX21, NOH61

Tested Applications

WB

Protein ID

20139238

Physical Properties

Liquid

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