POLA2 Antibody

Product Specifications

Background

POLA2 may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity) .

NCBI Gene ID

23649

Swiss Prot

Q14181

Accession Number

Q14181

Host

Rabbit

Reactivity

Human

Immunogen

This POLA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of human POLA2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

POLA2

NCBI Official Name

DNA polymerase alpha subunit B

NCBI Organism

Homo sapiens

Background Reference 01

Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)

Background Reference 02

Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

Background Reference 03

Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

Background Reference 04

Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

Other Product Names

DNA polymerase alpha subunit B, DNA polymerase alpha 70 kDa subunit, POLA2

Tested Applications

Protein ID

90110415

Physical Properties

Liquid

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