LMBR1 Antibody

Product Specifications

Background

This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.

NCBI Gene ID

64327

Swiss Prot

Q8WVP7

Accession Number

Q8WVP7

Host

Rabbit

Reactivity

Human

Immunogen

This LMBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human LMBR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LMBR1

NCBI Official Name

Limb region 1 protein homolog

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Farooq, M., et al. Eur. J. Hum. Genet. 18 (6) :733-736 (2010)

Background Reference 03

Rutsch, F., et al. Nat. Genet. 41 (2) :234-239 (2009)

Background Reference 04

He, F., et al. PLoS ONE (8), E2948 (2008) :

Other Product Names

Limb region 1 protein homolog, Differentiation-related gene 14 protein, LMBR1, C7orf2, DIF14

Tested Applications

Protein ID

74730878

Physical Properties

Liquid

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