AP4B1 Antibody

Product Specifications

Background

The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243) .

NCBI Gene ID

10717

Swiss Prot

Q9Y6B7

Accession Number

Q9Y6B7

Host

Rabbit

Reactivity

Human

Immunogen

This AP4B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the Central region of human AP4B1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AP4B1

NCBI Official Name

AP-4 complex subunit beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 02

Cayrol, C., et al. Biochem. Biophys. Res. Commun. 298 (5) :720-730 (2002)

Background Reference 03

Takatsu, H., et al. Biochem. Biophys. Res. Commun. 284 (4) :1083-1089 (2001)

Background Reference 04

Hirst, J., et al. Mol. Biol. Cell 10 (8) :2787-2802 (1999)

Other Product Names

AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1, Beta subunit of AP-4, Beta4-adaptin, AP4B1