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CCBE1 Antibody

Product Specifications

Background

This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans.

NCBI Gene ID

147372

Swiss Prot

Q6UXH8

Accession Number

Q6UXH8

Host

Rabbit

Reactivity

Human

Immunogen

This CCBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human CCBE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCBE1

NCBI Official Name

Collagen and calcium-binding EGF domain-containing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Connell, F., et al. Hum. Genet. 127 (2) :231-241 (2010)

Background Reference 03

Barton, C.A., et al. Br. J. Cancer 102 (1) :87-96 (2010)

Background Reference 04

Alders, M., et al. Nat. Genet. 41 (12) :1272-1274 (2009)

Other Product Names

Collagen and calcium-binding EGF domain-containing protein 1, Full of fluid protein homolog, CCBE1, KIAA1983

Tested Applications

WB

Protein ID

74738220

Physical Properties

Liquid

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