REXO2 Antibody
Product Specifications
Background
Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.
NCBI Gene ID
25996
Swiss Prot
Q9Y3B8
Accession Number
Q9Y3B8
Host
Rabbit
Reactivity
Human
Immunogen
This REXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-157 amino acids from the Central region of human REXO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
REXO2
NCBI Official Name
Oligoribonuclease, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Young Park, A., et al. Protein Expr. Purif. 57 (2) :180-187 (2008)
Background Reference 02
Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)
Background Reference 03
Ito, S., et al. Photochem. Photobiol. 80 (2) :281-285 (2004)
Background Reference 04
Simpson, J.C., et al. EMBO Rep. 1 (3) :287-292 (2000)
Other Product Names
Oligoribonuclease, mitochondrial, 31--, RNA exonuclease 2 homolog, Small fragment nuclease, REXO2, SFN, SMFN
Tested Applications
WB
Protein ID
116242694
Physical Properties
Liquid
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