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BIKE Antibody

Product Specifications

Background

BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.

NCBI Gene ID

55589

Swiss Prot

Q9NSY1

Accession Number

Q9NSY1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BIKE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-291 amino acids from the Central region of human BIKE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

129 kDa

Fragment

Rabbit Ig

Symbol

BMP2K

NCBI Official Name

BMP-2-inducible protein kinase

NCBI Organism

Homo sapiens

Background Reference 01

Kearns, A.E., et al., J. Biol. Chem. 276 (45) :42213-42218 (2001) .

Background Reference 02

Hoffmann, A., et al., Crit. Rev. Eukaryot. Gene Expr. 11 (1-3), 23-45 (2001) .

Other Product Names

BMP-2-inducible protein kinase, BIKe, BMP2K, BIKE

Tested Applications

WB, IHC-P

Protein ID

34222653

Physical Properties

Liquid

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