BIKE Antibody
Product Specifications
Background
BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.
NCBI Gene ID
55589
Swiss Prot
Q9NSY1
Accession Number
Q9NSY1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This BIKE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-291 amino acids from the Central region of human BIKE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
129 kDa
Fragment
Rabbit Ig
Symbol
BMP2K
NCBI Official Name
BMP-2-inducible protein kinase
NCBI Organism
Homo sapiens
Background Reference 01
Kearns, A.E., et al., J. Biol. Chem. 276 (45) :42213-42218 (2001) .
Background Reference 02
Hoffmann, A., et al., Crit. Rev. Eukaryot. Gene Expr. 11 (1-3), 23-45 (2001) .
Other Product Names
BMP-2-inducible protein kinase, BIKe, BMP2K, BIKE
Tested Applications
WB, IHC-P
Protein ID
34222653
Physical Properties
Liquid
Curated Selection
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