PDGFC Antibody
Product Specifications
Background
Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.
NCBI Gene ID
56034
Swiss Prot
Q9NRA1
Accession Number
Q9NRA1
Host
Rabbit
Reactivity
Human
Immunogen
This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-045
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
PDGFC
NCBI Official Name
Platelet-derived growth factor C
NCBI Organism
Homo sapiens
Background Reference 01
Fang, L., et al., Arterioscler. Thromb. Vasc. Biol. 24 (4) :787-792 (2004) . Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) . Eitner, F., et al., J. Am. Soc. Nephrol. 14 (5) :1145-1153 (2003) . Reigstad, L.J., et al., J. Biol. Chem. 278 (19) :17114-17120 (2003) . Zwerner, J.P., et al., Oncogene 21 (24) :3847-3854 (2002) .
Other Product Names
Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, Platelet-derived growth factor C, latent form, PDGFC latent form, Platelet-derived growth factor C, receptor-binding form, PDGFC receptor-binding form, PDGFC, SCDGF
Tested Applications
WB, IHC-P
Protein ID
205830662
Physical Properties
Liquid
Curated Selection
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