PDGFC Antibody

Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.

This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fang, L., et al., Arterioscler. Thromb. Vasc. Biol. 24 (4) :787-792 (2004) . Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) . Eitner, F., et al., J. Am. Soc. Nephrol. 14 (5) :1145-1153 (2003) . Reigstad, L.J., et al., J. Biol. Chem. 278 (19) :17114-17120 (2003) . Zwerner, J.P., et al., Oncogene 21 (24) :3847-3854 (2002) .

Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, Platelet-derived growth factor C, latent form, PDGFC latent form, Platelet-derived growth factor C, receptor-binding form, PDGFC receptor-binding form, PDGFC, SCDGF