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PDGFC Antibody

Product Specifications

Background

Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.

NCBI Gene ID

56034

Swiss Prot

Q9NRA1

Accession Number

Q9NRA1

Host

Rabbit

Reactivity

Human

Immunogen

This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-045

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

PDGFC

NCBI Official Name

Platelet-derived growth factor C

NCBI Organism

Homo sapiens

Background Reference 01

Fang, L., et al., Arterioscler. Thromb. Vasc. Biol. 24 (4) :787-792 (2004) . Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) . Eitner, F., et al., J. Am. Soc. Nephrol. 14 (5) :1145-1153 (2003) . Reigstad, L.J., et al., J. Biol. Chem. 278 (19) :17114-17120 (2003) . Zwerner, J.P., et al., Oncogene 21 (24) :3847-3854 (2002) .

Other Product Names

Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, Platelet-derived growth factor C, latent form, PDGFC latent form, Platelet-derived growth factor C, receptor-binding form, PDGFC receptor-binding form, PDGFC, SCDGF

Tested Applications

WB, IHC-P

Protein ID

205830662

Physical Properties

Liquid

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