ZKSCAN1 Antibody

Product Specifications

Background

The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]) . Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM].

NCBI Gene ID

7586

Swiss Prot

P17029

Accession Number

P17029

Host

Rabbit

Reactivity

Human

Immunogen

This ZKSCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-265 amino acids from the Central region of human ZKSCAN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

64 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZKSCAN1

NCBI Official Name

Zinc finger protein with KRAB and SCAN domains 1

NCBI Organism

Homo sapiens

Background Reference 01

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Jikuya, H., et al. DNA Res. 10 (1) :49-57 (2003)

Other Product Names

Zinc finger protein with KRAB and SCAN domains 1, Zinc finger protein 139, Zinc finger protein 36, Zinc finger protein KOX18, ZKSCAN1, KOX18, ZNF139, ZNF36