CDC14A Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq].
NCBI Gene ID
8556
Swiss Prot
Q9UNH5
Accession Number
Q9UNH5
Host
Rabbit
Reactivity
Human
Immunogen
This CDC14A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human CDC14A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDC14A
NCBI Official Name
Dual specificity protein phosphatase CDC14A
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 03
Mocciaro, A., et al. J. Cell Biol. 189 (4) :631-639 (2010)
Background Reference 04
Song, S.Y., et al. APMIS 118 (5) :389-393 (2010)
Other Product Names
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Tested Applications
WB
Protein ID
55976620
Physical Properties
Liquid
Frequently Asked Questions
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