DCP1A Antibody
Product Specifications
Background
Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
NCBI Gene ID
55802
Swiss Prot
Q9NPI6
Accession Number
Q9NPI6
Host
Rabbit
Reactivity
Human
Immunogen
This DCP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the N-terminal region of human DCP1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DCP1A
NCBI Official Name
MRNA-decapping enzyme 1A
NCBI Organism
Homo sapiens
Other Product Names
MRNA-decapping enzyme 1A, 3---, Smad4-interacting transcriptional co-activator, Transcription factor SMIF, DCP1A, SMIF
Tested Applications
WB
Protein ID
296434475
Physical Properties
Liquid
Curated Selection
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