PPP1R13B Antibody

Product Specifications

Background

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

NCBI Gene ID

23368

Swiss Prot

Q96KQ4

Accession Number

Q96KQ4

Host

Rabbit

Reactivity

Human

Immunogen

This PPP1R13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-652 amino acids from the Central region of human PPP1R13B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

120 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP1R13B

NCBI Official Name

Apoptosis-stimulating of p53 protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Figl, A., et al. Mutat. Res. 702 (1) :8-16 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Zhao, J., et al. Hepatology 51 (1) :142-153 (2010)

Background Reference 04

Agirre, X., et al. Oncogene 25 (13) :1862-1870 (2006)

Other Product Names

Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B, PPP1R13B, ASPP1, KIAA0771

Tested Applications

Protein ID

296439434

Physical Properties

Liquid

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