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TBX2 Antibody

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.

NCBI Gene ID

6909

Swiss Prot

Q13207

Accession Number

Q13207

Host

Rabbit

Reactivity

Human

Immunogen

This TBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the Central region of human TBX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

75 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TBX2

NCBI Official Name

T-box transcription factor TBX2

NCBI Organism

Homo sapiens

Background Reference 01

Vance, K.W., et al. Mol. Biol. Cell 21 (15) :2770-2779 (2010)

Background Reference 02

Radio, F.C., et al. Am. J. Med. Genet.152A (8), 2061-2066 (2010) :

Background Reference 03

Kottgen, A., et al. Nat. Genet. 42 (5) :376-384 (2010)

Background Reference 04

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

Other Product Names

T-box transcription factor TBX2, T-box protein 2, TBX2

Tested Applications

WB

Protein ID

294862490

Physical Properties

Liquid

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