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H1FOO Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.

NCBI Gene ID

132243

Swiss Prot

Q8IZA3

Accession Number

Q8IZA3

Host

Rabbit

Reactivity

Human

Immunogen

This H1FOO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human H1FOO.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-007

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

H1FOO

NCBI Official Name

Histone H1oo

NCBI Organism

Homo sapiens

Background Reference 01

Mizusawa, Y., et al. Fertil. Steril. 93 (4) :1134-1141 (2010)

Background Reference 02

Tanaka, M., et al. Biol. Reprod. 72 (1) :135-142 (2005)

Background Reference 03

Teranishi, T., et al. Dev. Biol. 266 (1) :76-86 (2004)

Background Reference 04

Gao, S., et al. Dev. Biol. 266 (1) :62-75 (2004)

Other Product Names

Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1, H1FOO, H1OO, OSH1

Tested Applications

WB

Protein ID

74762503

Physical Properties

Liquid

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