TRIM68 Antibody

Product Specifications

Background

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.

NCBI Gene ID

55128

Swiss Prot

Q6AZZ1

Accession Number

Q6AZZ1

Host

Rabbit

Reactivity

Human

Immunogen

This TRIM68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-411 amino acids from the C-terminal region of human TRIM68.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TRIM68

NCBI Official Name

E3 ubiquitin-protein ligase TRIM68

NCBI Organism

Homo sapiens

Background Reference 01

Malhotra, A., et al. Diabetes Metab. Res. Rev. 25 (8) :740-747 (2009)

Background Reference 02

Miyajima, N., et al. Cancer Res. 68 (9) :3486-3494 (2008)

Background Reference 03

Chang, G.T., et al. Eur. J. Cancer 37 (16) :2129-2134 (2001)

Background Reference 04

Billaut-Mulot, O., et al. J. Clin. Invest. 108 (6) :861-869 (2001)

Other Product Names

E3 ubiquitin-protein ligase TRIM68, 632-, RING finger protein 137, SSA protein SS-56, SS-56, Tripartite motif-containing protein 68, TRIM68, GC109, RNF137, SS56