BCL7B Antibody

Product Specifications

Background

This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene.

NCBI Gene ID

9275

Swiss Prot

Q9BQE9

Accession Number

Q9BQE9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BCL7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the C-terminal region of human BCL7B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Symbol

BCL7B

NCBI Official Name

B-cell CLL/lymphoma 7 protein family member B

NCBI Organism

Homo sapiens

Background Reference 01

Fontaine-Bisson, B., et al. Diabetologia 53 (10) :2155-2162 (2010)

Background Reference 02

Kathiresan, S., et al. Nat. Genet. 40 (2) :189-197 (2008)

Background Reference 03

Willer, C.J., et al. Nat. Genet. 40 (2) :161-169 (2008)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

B-cell CLL/lymphoma 7 protein family member B, Hom s 3, BCL7B

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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