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DOK5 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.

NCBI Gene ID

55816

Swiss Prot

Q9P104

Accession Number

Q9P104

Host

Rabbit

Reactivity

Human

Immunogen

This DOK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human DOK5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DOK5

NCBI Official Name

Docking protein 5

NCBI Organism

Homo sapiens

Background Reference 01

Liu, X., et al.Am Acad Child Adolesc Psychiatry 49 (1) :33-41 (2010)

Background Reference 02

Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :

Background Reference 03

Shi, L., et al. Cell. Signal. 18 (11) :1995-2003 (2006)

Background Reference 04

Cai, D., et al. J. Biol. Chem. 278 (28) :25323-25330 (2003)

Other Product Names

Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180

Tested Applications

WB

Protein ID

26393190

Physical Properties

Liquid

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