GCNT1 Antibody

Product Specifications

Background

This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3 (GlcNAc beta 1-6) GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI Gene ID

2650

Swiss Prot

Q02742

Accession Number

Q02742

Host

Rabbit

Reactivity

Human

Immunogen

This GCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human GCNT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GCNT1

NCBI Official Name

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Hatakeyama, S., et al. Int. J. Cancer 127 (5) :1052-1059 (2010)

Background Reference 02

Brockhausen, I., et al. Biochim. Biophys. Acta 1790 (10) :1244-1257 (2009)

Background Reference 03

St Hill, C.A., et al. BMC Cancer 9, 79 (2009) :

Background Reference 04

Nagaraj, S., et al. Pancreas 37 (3) :321-327 (2008)

Other Product Names

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT, Core 2 GNT, GCNT1, NACGT2