CBX2 Antibody
Product Specifications
Background
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
NCBI Gene ID
84733
Swiss Prot
Q14781
Accession Number
Q14781
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the Central region of human CBX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-983
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CBX2
NCBI Official Name
Chromobox protein homolog 2
NCBI Organism
Homo sapiens
Background Reference 01
Biason-Lauber, A., et al. Am. J. Hum. Genet. 84 (5) :658-663 (2009)
Background Reference 02
Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)
Background Reference 03
Agrawal, N., et al. PLoS ONE (12), E4032 (2008) :
Background Reference 04
Garcia, E., et al. EMBO J. 18 (12) :3404-3418 (1999)
Other Product Names
Chromobox protein homolog 2, CBX2
Tested Applications
WB
Protein ID
77416853
Physical Properties
Liquid
Curated Selection
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