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ZFYVE27 Antibody

Product Specifications

Background

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.

NCBI Gene ID

118813

Swiss Prot

Q5T4F4

Accession Number

Q5T4F4

Host

Rabbit

Reactivity

Human

Immunogen

This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ZFYVE27.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZFYVE27

NCBI Official Name

Protrudin

NCBI Organism

Homo sapiens

Background Reference 01

Saita, S., et al. J. Biol. Chem. 284 (20) :13766-13777 (2009)

Background Reference 02

Martignoni, M., et al. Am. J. Hum. Genet. 83 (1) :127-128 (2008)

Background Reference 03

Shirane, M., et al. Science 314 (5800) :818-821 (2006)

Background Reference 04

Mannan, A.U., et al. Am. J. Hum. Genet. 79 (2) :351-357 (2006)

Other Product Names

Protrudin, Zinc finger FYVE domain-containing protein 27, ZFYVE27

Tested Applications

WB

Protein ID

74744927

Physical Properties

Liquid

Frequently Asked Questions

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