ZFYVE27 Antibody

Product Specifications

Background

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.

NCBI Gene ID

118813

Swiss Prot

Q5T4F4

Accession Number

Q5T4F4

Host

Rabbit

Reactivity

Human

Immunogen

This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ZFYVE27.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZFYVE27

NCBI Official Name

Protrudin

NCBI Organism

Homo sapiens

Background Reference 01

Saita, S., et al. J. Biol. Chem. 284 (20) :13766-13777 (2009)

Background Reference 02

Martignoni, M., et al. Am. J. Hum. Genet. 83 (1) :127-128 (2008)

Background Reference 03

Shirane, M., et al. Science 314 (5800) :818-821 (2006)

Background Reference 04

Mannan, A.U., et al. Am. J. Hum. Genet. 79 (2) :351-357 (2006)

Other Product Names

Protrudin, Zinc finger FYVE domain-containing protein 27, ZFYVE27

Tested Applications

Protein ID

74744927

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

A22594-100UG 100 µg

H2AFZ Antibody

Ask

View Details

GTR15159997 1 Vial

Lentiviral human NANS shRNA (UAS) - Lentiviral human NANS shRNA (UAS, RFP) plasmid

Ask

View Details

RR213764L3 10 µg

Pnrc1 (NM_173322) Rat Tagged Lenti ORF Clone

Ask

View Details

PHC36501 100 μg

Anti-Human IGFBP1 Polyclonal Antibody

Ask

View Details

RC200725L4 10 µg

Superoxide Dismutase 1 (SOD1) (NM_000454) Human Tagged Lenti ORF Clone

Ask

View Details