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PTDSS1 Antibody

Product Specifications

Background

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]) .

NCBI Gene ID

9791

Swiss Prot

P48651

Accession Number

P48651

Host

Rabbit

Reactivity

Human

Immunogen

This PTDSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human PTDSS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PTDSS1

NCBI Official Name

Phosphatidylserine synthase 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Tomohiro, S., et al. Biochem. J. 418 (2) :421-429 (2009)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Sturbois-Balcerzak, B., et al. J. Biol. Chem. 276 (11) :8205-8212 (2001)

Other Product Names

Phosphatidylserine synthase 1, PSS-1, PtdSer synthase 1, Serine-exchange enzyme I, PTDSS1, KIAA0024, PSSA

Tested Applications

WB

Protein ID

1346881

Physical Properties

Liquid

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