TPBG Antibody
Product Specifications
Background
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq].
NCBI Gene ID
7162
Swiss Prot
Q13641
Accession Number
Q13641
Host
Rabbit
Reactivity
Human
Immunogen
This TPBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human TPBG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-957
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TPBG
NCBI Official Name
Trophoblast glycoprotein
NCBI Organism
Homo sapiens
Background Reference 01
Elkord, E., et al. J. Immunother. 31 (9) :820-829 (2008)
Background Reference 02
Shingler, W.H., et al. Int. Immunol. 20 (8) :1057-1066 (2008)
Background Reference 03
Okazaki, S., et al. Obstet Gynecol 110 (5) :1130-1136 (2007)
Background Reference 04
Ward, C.M., et al. Exp. Cell Res. 312 (10) :1713-1726 (2006)
Other Product Names
Trophoblast glycoprotein, 5T4 oncofetal antigen, 5T4 oncofetal trophoblast glycoprotein, 5T4 oncotrophoblast glycoprotein, M6P1, Wnt-activated inhibitory factor 1, WAIF1, TPBG, 5T4
Tested Applications
WB
Protein ID
73621980
Physical Properties
Liquid
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