POLR1E Antibody
Product Specifications
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (By similarity) .
NCBI Gene ID
64425
Swiss Prot
Q9GZS1
Accession Number
Q9GZS1
Host
Rabbit
Reactivity
Human
Immunogen
This POLR1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-198 amino acids from the Central region of human POLR1E.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-944
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
POLR1E
NCBI Official Name
DNA-directed RNA polymerase I subunit RPA49
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 03
Percipalle, P., et al. EMBO Rep. 7 (5) :525-530 (2006)
Background Reference 04
Yamamoto, K., et al. Mol. Cell. Biol. 24 (14) :6338-6349 (2004)
Other Product Names
DNA-directed RNA polymerase I subunit RPA49, RNA polymerase I subunit A49, DNA-directed RNA polymerase I subunit E, RNA polymerase I-associated factor 1, RNA polymerase I-associated factor 53, POLR1E, PAF53, PRAF1
Tested Applications
WB
Protein ID
62901107
Physical Properties
Liquid
Curated Selection
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