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MPI Antibody

Product Specifications

Background

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.

NCBI Gene ID

4351

Swiss Prot

P34949

Accession Number

P34949

Host

Rabbit

Reactivity

Human

Immunogen

This MPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human MPI.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-940

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MPI

NCBI Official Name

Mannose-6-phosphate isomerase

NCBI Organism

Homo sapiens

Background Reference 01

Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Xiao, J., et al. J. Mol. Graph. Model. 25 (3) :289-295 (2006)

Background Reference 04

Vuillaumier-Barrot, S., et al. J. Med. Genet. 39 (11) :849-851 (2002)

Other Product Names

Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI, MPI, PMI1

Tested Applications

WB

Protein ID

462567

Physical Properties

Liquid

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