IL28 Antibody
Product Specifications
Background
IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA) .
NCBI Gene ID
282616
Swiss Prot
Q8IZJ0
Accession Number
Q8IZJ0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IL28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-92 amino acids from the Central region of human IL28.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IFNL2
NCBI Official Name
Interferon lambda-2
NCBI Organism
Homo sapiens
Background Reference 01
Kotenko, S.V., et al., Nat. Immunol. 4 (1) :69-77 (2003) .
Background Reference 02
Sheppard, P., et al., Nat. Immunol. 4 (1) :63-68 (2003) .
Other Product Names
Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, IFNL2, IL28A, ZCYTO20
Tested Applications
WB
Protein ID
55976531
Physical Properties
Liquid
Curated Selection
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