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IL28 Antibody

Product Specifications

Background

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA) .

NCBI Gene ID

282616

Swiss Prot

Q8IZJ0

Accession Number

Q8IZJ0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This IL28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-92 amino acids from the Central region of human IL28.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

IFNL2

NCBI Official Name

Interferon lambda-2

NCBI Organism

Homo sapiens

Background Reference 01

Kotenko, S.V., et al., Nat. Immunol. 4 (1) :69-77 (2003) .

Background Reference 02

Sheppard, P., et al., Nat. Immunol. 4 (1) :63-68 (2003) .

Other Product Names

Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, IFNL2, IL28A, ZCYTO20

Tested Applications

WB

Protein ID

55976531

Physical Properties

Liquid

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