Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ULBP2 Antibody

Product Specifications

Background

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

NCBI Gene ID

80328

Swiss Prot

Q9BZM5

Accession Number

Q9BZM5

Host

Rabbit

Reactivity

Human

Immunogen

This ULBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human ULBP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-936

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ULBP2

NCBI Official Name

NKG2D ligand 2

NCBI Organism

Homo sapiens

Background Reference 01

McGilvray, R.W., et al. Int. J. Cancer 127 (6) :1412-1420 (2010)

Background Reference 02

Nuckel, H., et al. Leukemia 24 (6) :1152-1159 (2010)

Background Reference 03

Antoun, A., et al. Hum. Immunol. 71 (6) :610-620 (2010)

Background Reference 04

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Other Product Names

NKG2D ligand 2, N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2, N2DL2, RAET1H

Tested Applications

WB

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Anti-Human NAT1 pAb
PA9278-01 50 μL

Rabbit Anti-Human NAT1 pAb

Ask
View Details
Rabbit Anti-Human NAT1 pAb
PA9278-02 100 μL

Rabbit Anti-Human NAT1 pAb

Ask
View Details
CMTM7-set siRNA/shRNA/RNAi Lentivector (Human)
16438091 4 x 500 ng

CMTM7-set siRNA/shRNA/RNAi Lentivector (Human)

Ask
View Details
Human Plastin 3 (PLS3) ELISA Kit
MBS9312912-01 48 Well

Human Plastin 3 (PLS3) ELISA Kit

Ask
View Details
Human Plastin 3 (PLS3) ELISA Kit
MBS9312912-02 96 Well

Human Plastin 3 (PLS3) ELISA Kit

Ask
View Details
Human Plastin 3 (PLS3) ELISA Kit
MBS9312912-03 5x 96 Well

Human Plastin 3 (PLS3) ELISA Kit

Ask
View Details