MMRN1 Antibody

Product Specifications

Background

Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.

NCBI Gene ID

22915

Swiss Prot

Q13201

Accession Number

Q13201

Host

Rabbit

Reactivity

Human

Immunogen

This MMRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human MMRN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

138 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MMRN1

NCBI Official Name

Multimerin-1

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 02

Simon-Sanchez, J., et al. Nat. Genet. 41 (12) :1308-1312 (2009)

Background Reference 03

Tasneem, S., et al. J. Thromb. Haemost. 7 (4) :685-692 (2009)

Background Reference 04

Jeimy, S.B., et al. Thromb. Haemost. 100 (6) :1058-1067 (2008)

Other Product Names

Multimerin-1, EMILIN-4, Elastin microfibril interface located protein 4, Elastin microfibril interfacer 4, Endothelial cell multimerin, Platelet glycoprotein Ia*, 155 kDa platelet multimerin, p-155, p155, MMRN1, ECM, EMILIN4, GPIA*, MMRN