TPPP Antibody

Product Specifications

Background

TPPP may play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

NCBI Gene ID

11076

Swiss Prot

O94811

Accession Number

O94811

Host

Rabbit

Reactivity

Human

Immunogen

This TPPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-75 amino acids from the Central region of human TPPP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit IgG

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TPPP

NCBI Official Name

Tubulin polymerization-promoting protein

NCBI Organism

Homo sapiens

Background Reference 01

Tokesi, N., et al. J. Biol. Chem. 285 (23) :17896-17906 (2010)

Background Reference 02

McGovern, D.P., et al. Nat. Genet. 42 (4) :332-337 (2010)

Background Reference 03

Sun, M., et al. Cell. Signal. 21 (12) :1857-1865 (2009)

Background Reference 04

Ovadi, J., et al. Bioessays 31 (6) :676-686 (2009)

Other Product Names

Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p24, p25-alpha, TPPP, TPPP1

Tested Applications

Physical Properties

Liquid

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