IL-27 Antibody
Product Specifications
Background
IL-27 is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
NCBI Gene ID
53342
Swiss Prot
Q8TAD2
Accession Number
Q8TAD2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IL-27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-87 amino acids from the Central region of human IL-27.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
IL17D
NCBI Official Name
Interleukin-17D
NCBI Organism
Homo sapiens
Background Reference 01
Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .
Background Reference 02
Starnes, T., et al., J. Immunol. 169 (2) :642-646 (2002) .
Other Product Names
Interleukin-17D, IL-17D, Interleukin-27, IL-27, IL17D, IL27
Tested Applications
WB, IHC-P, Flow
Protein ID
46576614
Physical Properties
Liquid
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