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FBXO31 Antibody

Product Specifications

Background

Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM].

NCBI Gene ID

79791

Swiss Prot

Q5XUX0

Accession Number

Q5XUX0

Host

Rabbit

Reactivity

Human

Immunogen

This FBXO31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human FBXO31.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-919

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FBXO31

NCBI Official Name

F-box only protein 31

NCBI Organism

Homo sapiens

Background Reference 01

Rivadeneira, F., et al. Nat. Genet. 41 (11) :1199-1206 (2009)

Background Reference 02

Santra, M.K., et al. Nature 459 (7247) :722-725 (2009)

Background Reference 03

Kumar, R., et al. Cancer Res. 65 (24) :11304-11313 (2005)

Background Reference 04

Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)

Other Product Names

F-box only protein 31, FBXO31, FBX14, FBX31

Tested Applications

WB

Protein ID

146345419

Physical Properties

Liquid

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