LIN9 Antibody
Product Specifications
Background
LIN9 acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
NCBI Gene ID
286826
Swiss Prot
Q5TKA1
Accession Number
Q5TKA1
Host
Rabbit
Reactivity
Human
Immunogen
This LIN9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human LIN9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:500
Symbol
LIN9
NCBI Official Name
Protein lin-9 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 02
Arking, D.E., et al. PLoS ONE (3), E9879 (2010) :
Background Reference 03
Pilkinton, M., et al. Oncogene 26 (54) :7535-7543 (2007)
Background Reference 04
Osterloh, L., et al. EMBO J. 26 (1) :144-157 (2007)
Other Product Names
Protein lin-9 homolog, HuLin-9, hLin-9, Beta subunit-associated regulator of apoptosis, TUDOR gene similar protein, Type I interferon receptor beta chain-associated protein, pRB-associated protein, LIN9, BARA, TGS
Tested Applications
WB
Protein ID
74708186
Physical Properties
Liquid
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