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ANXA9 Antibody

Product Specifications

Background

The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.

NCBI Gene ID

8416

Swiss Prot

O76027

Accession Number

O76027

Host

Rabbit

Reactivity

Human

Immunogen

This ANXA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-235 amino acids from the Central region of human ANXA9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ANXA9

NCBI Official Name

Annexin A9

NCBI Organism

Homo sapiens

Background Reference 01

Kottgen, A., et al. Nat. Genet. 42 (5) :376-384 (2010)

Background Reference 02

Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

Background Reference 03

Goebeler, V., et al. FEBS Lett. 546 (2-3), 359-364 (2003) :

Background Reference 04

Nguyen, V.T., et al. J. Biol. Chem. 275 (38) :29466-29476 (2000)

Other Product Names

Annexin A9, Annexin XXXI, Annexin-31, Annexin-9, Pemphaxin, ANXA9, ANX31

Tested Applications

WB

Physical Properties

Liquid

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