CRTAP Antibody
Product Specifications
Background
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
NCBI Gene ID
10491
Swiss Prot
O75718
Accession Number
O75718
Host
Rabbit
Reactivity
Human
Immunogen
This CRTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-59 amino acids from the N-terminal region of human CRTAP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
CRTAP
NCBI Official Name
Cartilage-associated protein
NCBI Organism
Homo sapiens
Background Reference 01
Morello, R., et al. Curr Osteoporos Rep 8 (2) :77-83 (2010)
Background Reference 02
Li, G.H., et al. Osteoporos Int 21 (6) :1009-1020 (2010)
Background Reference 03
Fratzl-Zelman, N., et al. Bone 46 (3) :820-826 (2010)
Background Reference 04
Chang, W., et al. Hum. Mol. Genet. 19 (2) :223-234 (2010)
Other Product Names
Cartilage-associated protein, CRTAP, CASP
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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