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CRLF1 Antibody

Product Specifications

Background

This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq].

NCBI Gene ID

9244

Swiss Prot

O75462

Accession Number

O75462

Host

Rabbit

Reactivity

Human

Immunogen

This CRLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-283 amino acids from the Central region of human CRLF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-910

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CRLF1

NCBI Official Name

Cytokine receptor-like factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Tsuritani, K., et al. Calcif. Tissue Int. 86 (1) :47-57 (2010)

Background Reference 02

Crisponi, L., et al. Am. J. Hum. Genet. 80 (5) :971-981 (2007)

Background Reference 03

Dagoneau, N., et al. Am. J. Hum. Genet. 80 (5) :966-970 (2007)

Background Reference 04

Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)

Other Product Names

Cytokine receptor-like factor 1, Cytokine-like factor 1, CLF-1, ZcytoR5, CRLF1

Tested Applications

WB

Physical Properties

Liquid

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