SUOX Antibody

Product Specifications

Background

Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.

NCBI Gene ID

6821

Swiss Prot

P51687

Accession Number

P51687

Host

Rabbit

Reactivity

Human

Immunogen

This SUOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-187 amino acids from the Central region of human SUOX.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SUOX

NCBI Official Name

Sulfite oxidase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Rajapakshe, A., et al. Biochemistry 49 (25) :5154-5159 (2010)

Background Reference 02

Johnson-Winters, K., et al. Biochemistry 49 (6) :1290-1296 (2010)

Background Reference 03

Neumann, M., et al. FEBS J. 275 (22) :5678-5689 (2008)

Background Reference 04

Astashkin, A.V., et al. J. Am. Chem. Soc. 130 (26) :8471-8480 (2008)

Other Product Names

Sulfite oxidase, mitochondrial, SUOX

Tested Applications

Protein ID

152031695

Physical Properties

Liquid

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