SAP30 Antibody
Product Specifications
Background
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq].
NCBI Gene ID
8819
Swiss Prot
O75446
Accession Number
O75446
Host
Rabbit
Reactivity
Human
Immunogen
This SAP30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human SAP30.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SAP30
NCBI Official Name
Histone deacetylase complex subunit SAP30
NCBI Organism
Homo sapiens
Background Reference 01
Brandt, S., et al. Int. J. Biochem. Cell Biol. 42 (9) :1472-1481 (2010)
Background Reference 02
Viiri, K.M., et al. Mol. Cell. Biol. 29 (2) :342-356 (2009)
Background Reference 03
Sichtig, N., et al. Arch. Biochem. Biophys. 467 (1) :67-75 (2007)
Background Reference 04
Szafranski, K., et al. Genome Biol. (8), R154 (2007) :
Other Product Names
HGNC:10532
Tested Applications
WB
Physical Properties
Liquid
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