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TJP2 Antibody

Product Specifications

Background

This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutation in this gene have been identified in patients with hypercholanemia. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

9414

Swiss Prot

Q9UDY2

Accession Number

Q9UDY2

Host

Rabbit

Reactivity

Human

Immunogen

This TJP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 981-1009 amino acids from the C-terminal region of human TJP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-905

Calculated Molecular Weight

134 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TJP2

NCBI Official Name

Tight junction protein ZO-2

NCBI Organism

Homo sapiens

Background Reference 01

Lechuga, S., et al. Exp. Cell Res. 316 (19) :3124-3139 (2010)

Background Reference 02

Remue, E., et al. FEBS Lett. 584 (19) :4175-4180 (2010)

Background Reference 03

Walsh, T., et al. Am. J. Hum. Genet. 87 (1) :101-109 (2010)

Background Reference 04

Meerschaert, K., et al. Cell. Mol. Life Sci. 66 (24) :3951-3966 (2009)

Other Product Names

Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2, TJP2, X104, ZO2

Tested Applications

WB

Protein ID

317373313

Physical Properties

Liquid

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