HRH4 Antibody

Product Specifications

Background

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

59340

Swiss Prot

Q9H3N8

Accession Number

Q9H3N8

Host

Rabbit

Reactivity

Human

Immunogen

This HRH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the Central region of human HRH4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HRH4

NCBI Official Name

Histamine H4 receptor

NCBI Organism

Homo sapiens

Background Reference 01

Yu, B., et al. Br. J. Dermatol. 163 (5) :935-940 (2010)

Background Reference 02

Gschwandtner, M., et al. Allergy 65 (7) :840-849 (2010)

Background Reference 03

Yu, B., et al. Br. J. Dermatol. 162 (5) :1038-1043 (2010)

Background Reference 04

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Other Product Names

Histamine H4 receptor, H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144, HRH4, GPCR105

Tested Applications

Protein ID

14194819

Physical Properties

Liquid

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