FCN1 Antibody

Product Specifications

Background

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.

NCBI Gene ID

2219

Swiss Prot

O00602

Accession Number

O00602

Host

Rabbit

Reactivity

Human

Immunogen

This FCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human FCN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-889

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FCN1

NCBI Official Name

Ficolin-1

NCBI Organism

Homo sapiens

Background Reference 01

Honore, C., et al. J. Leukoc. Biol. 88 (1) :145-158 (2010)

Background Reference 02

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 03

Gout, E., et al. J. Biol. Chem. 285 (9) :6612-6622 (2010)

Background Reference 04

Wittenborn, T., et al.Innate Immun 2 (2) :167-180 (2010)

Other Product Names

Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, FCN1, FCNM

Tested Applications

Physical Properties

Liquid

Curated Selection

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FCN1 Antibody

Product Specifications

Background

NCBI Gene ID

Swiss Prot

Accession Number

Host

Reactivity

Immunogen

Clonality

Conjugation

Type

Field of Research

Purification

Concentration

Buffer

Modification

Shipping Conditions

Storage Conditions

Product Datasheet

Calculated Molecular Weight

Fragment

Applications Notes

Symbol

NCBI Official Name

NCBI Organism

Background Reference 01

Background Reference 02

Background Reference 03

Background Reference 04

Other Product Names

Tested Applications

Physical Properties

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