FCN1 Antibody
Product Specifications
Background
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.
NCBI Gene ID
2219
Swiss Prot
O00602
Accession Number
O00602
Host
Rabbit
Reactivity
Human
Immunogen
This FCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human FCN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FCN1
NCBI Official Name
Ficolin-1
NCBI Organism
Homo sapiens
Background Reference 01
Honore, C., et al. J. Leukoc. Biol. 88 (1) :145-158 (2010)
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Gout, E., et al. J. Biol. Chem. 285 (9) :6612-6622 (2010)
Background Reference 04
Wittenborn, T., et al.Innate Immun 2 (2) :167-180 (2010)
Other Product Names
Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, FCN1, FCNM
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
TA803999 100 µL
Cytokeratin 19 (KRT19) Mouse Monoclonal Antibody [Clone ID: OTI5G7]
Ask
View Details