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PAF1 Antibody

Product Specifications

Background

PAF1, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and CTR9 (MIM 609366) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]) . The PAF complex also has a role in histone monoubiquitination (Zhu et al., 2005 [PubMed 16307923]) .[supplied by OMIM].

NCBI Gene ID

54623

Swiss Prot

Q8N7H5

Accession Number

Q8N7H5

Host

Rabbit

Reactivity

Human

Immunogen

This PAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-467 amino acids from the C-terminal region of human PAF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-886

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PAF1

NCBI Official Name

RNA polymerase II-associated factor 1 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Muntean, A.G., et al. Cancer Cell 17 (6) :609-621 (2010)

Background Reference 02

Kim, J., et al. Cell 140 (4) :491-503 (2010)

Background Reference 03

Moniaux, N., et al. PLoS ONE (9), E7077 (2009) :

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

RNA polymerase II-associated factor 1 homolog, hPAF1, Pancreatic differentiation protein 2, PAF1, PD2

Tested Applications

WB

Protein ID

182670295

Physical Properties

Liquid

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