RGS11 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
NCBI Gene ID
8786
Swiss Prot
O94810
Accession Number
O94810
Host
Rabbit
Reactivity
Human
Immunogen
This RGS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RGS11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RGS11
NCBI Official Name
Regulator of G-protein signaling 11
NCBI Organism
Homo sapiens
Background Reference 01
Wang, J., et al. Carcinogenesis 31 (10) :1755-1761 (2010)
Background Reference 02
Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)
Background Reference 03
Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386 (1) :65-70 (2009)
Background Reference 04
Martin, J., et al. Nature 432 (7020) :988-994 (2004)
Other Product Names
Regulator of G-protein signaling 11, RGS11, RGS11
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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